Mesothelioma and Asbestos
Asbestos, a mineral that naturally occurs in the form of long, thin fibers. Workers who are exposed to asbestos regularly risk developing mesothelioma and other lung diseases of different types.
The symptoms of these diseases might not manifest for years after exposure to asbestos. Different asbestos types may cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma occurs in the outer lung lining, also known as the pleura. It is the most frequent form of mesothelioma and is responsible for 70 to 79% all diagnosed cases. The condition can cause chest pain, shortness of breathe, and a feeling of weightiness.
This type of cancer is often caused by exposure to asbestos, which is a collection of minerals made up of microscopic fibres. When inhaled, these fibers stick inside the lung and cause irritation which results in scarring and DNA mutations. The pleura covers the chest cavity and lungs This means that these irritations can affect both the lungs as well as a person's heart. Mesothelioma symptoms are usually not apparent until 30 to 50 years after exposure.
Shortness of breath and chest pain are the most common symptoms. Patients may also experience coughing, difficulty breathing, or chest tightness. Patients with this cancer have a history of disease that includes asbestos exposure at work. Construction, manufacturing, and shipbuilding are the most frequent jobs which put people at risk risk of developing pleural mesothelioma. People who served in the military are at higher risk due to the widespread use of asbestos in Navy vessels and bunkers for the Army.
The most popular staging method for pleural mesothelioma is the TNM (tumor, lymph nodes and metastases) staging system. The stage a patient has when they are diagnosed will aid their doctor in determining the best treatment plan for them. For instance, patients who have mesothelioma that is pleural in stage three or four have a worse prognosis than those in a lower stage. Mesothelioma in stage four is usually spread to the diaphragm, the liver or even a person's heart. This can make it more difficult to treat and increases the risk of complications for the patient.
Peritoneal Mesothelioma
Unlike pleural cancer, that develops in the lung's lining the peritoneal cancer is a result of a membrane that covers the abdominal cavity, including organs like the liver and intestines. As with pleural mesothelioma asbestos exposure is the cause of peritoneal mesothelioma. Only 300-500 cases are diagnosed each year this is less than pleural asbestosis.
As with pleural asbestosis symptoms can take years to show. Typically, patients experience abdominal pain and abdominal swelling. Symptoms of this type of mesothelioma may also include nausea or weight loss, as well as fever. Many of these symptoms could be misinterpreted as gastrointestinal issues which can lead to a mistaken diagnosis.
Typically, doctors can identify mesothelioma through an exhaustive health history and physical exam. They can also utilize imaging tests like X-rays, CT scans and PET/CT scans to help find mesothelioma. These tests can reveal tumors and other symptoms of cancer that aren't visible on an X-ray.
These tests enable doctors to diagnose mesothelioma, determine the stage and recommend treatment options. The stage is determined by the type of cell as well as whether the cancer has spread.
The most important mesothelioma-related risk factor is exposure to
asbestos attorney. People who have worked in
asbestos claim-containing jobs, such as plumbing or electrical work, or in construction, manufacturing and manufacturing, are more likely to develop the disease. Even if they do not work in these fields they could be exposed to asbestos through family members or other sources. Anyone who thinks they're at risk should consult an expert. A mesothelioma expert can help those who have a history with asbestos to learn more about their risk.
Risk Factors
Asbestos is the main risk factor for mesothelioma. It accounts for as much as 80percent of cases. Exposure to asbestos can happen as a result of work, military service or through living with a person who works with asbestos or has previously done such. When exposed to asbestos, small particles can be breathed into the lungs and abdomen. These particles irritate the linings of the abdomen, which causes cancerous cells to develop in the mesothelium. Mesothelioma can take anywhere between 15 and 60 years to develop after exposure to
asbestos attorney.
Other risk factors include smoking, genetics and aging. The people in their 40s or 50s are at greater risk of developing mesothelioma as compared to those who are younger or older. It takes mesothelioma 20-60 years to manifest cancer symptoms after the first exposure. It is important to keep in mind that mesothelioma can develop in those who have been exposed to asbestos case (
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asbestos claim exposure.
Smoking increases a person's chances of developing mesothelioma due to the fact that it damages the mesothelium, which makes it more vulnerable to asbestos. Additionally, mesothelioma can be worsened by certain diseases like asbestosis and pneumonia. Men are more likely to develop mesothelioma than women. This is due to the fact that men are more likely to be exposed to asbestos and endure a more exposure than women. Men are also more likely to have lived with someone who worked with asbestos and to have asbestos-containing fibers on their clothing. Women tend to have less exposure to asbestos and don't typically carry asbestos home on their clothes.
Diagnosis
It is difficult to diagnose mesothelioma due to its symptoms being often similar to other diseases. This is why patients are often mistakenly diagnosed.
The first step in identifying mesothelioma is for NYU Langone doctors to perform an examination of the body and take note of the medical history of the patient, including asbestos exposure. Doctors may also request an CT scan or chest X-ray in order to look for lumps, abnormalities, and evidence of exposure to asbestos. These include pleural plaques, thickened pleura and calcium deposits.
Other diagnostic tests include a magnetic resonance scan, or MRI test, that uses radio waves and magnets in order to produce a series of precise images of the inside of the body. A surgical biopsy is yet another method doctors use to diagnose mesothelioma. In a surgical biopsy doctors take a tiny part of tissue from the pleura or the peritoneum, to be further examined. A pathologist is then able to examine the tissue with microscopes to determine whether it is contaminated with cancerous cells.
The type of mesothelial cells involved, the malignant or benign nature of these cells, as well as the location, type and stage of the tumor, are used to categorize the disease. Certain mesothelioma types have an increased risk of metastasizing or spreading and it's crucial to determine the type of mesothelioma so doctors can treat it prior to it becoming out of control.
Doctors may also conduct laboratory tests on a tumor to identify specific genes, proteins or other elements that can help them describe the cancer's characteristics and plan treatment. These results are known as staging.
Treatment
A diagnosis of mesothelioma can be a frightening prospect. However, it's important to keep in mind that the cancer is treatable, particularly in its initial stages. Many people with mesothelioma live for years with the disease, without spreading to other areas of their body.
Asbestos exposure can cause mesothelioma by various mechanisms. Asbestos fibers, too small to be able to see or feel through the naked eye, can become airborne and cause irritation to the lining of the lungs (pleura). As time passes irritation leads to formation of scar tissue, which can cause changes in the structure of cells that can eventually grow into tumors.
The Pleura is a protective layer that covers the lungs, heart and abdomen. Mesothelium is made up of cells that react to asbestos, causing it to inflame and create scar tissue. These changes can cause mesothelioma cancers.
The signs of pleural mesothelioma can include breathlessness and chest pain as well as an accumulation of fluid in the lungs (pleural effusion). In rare instances the cancer may grow to the tissues surrounding the heart and reproductive organs.
If imaging scans show a possible mass in the stomach or lungs, a doctor will order biopsies. During the procedure, doctors take small amounts of the tumor or fluid for lab testing. The results will confirm the diagnosis of mesothelioma and indicate the best treatment option.
There are several types of mesothelioma treatments, including chemotherapy, surgery and immunotherapy. The majority of doctors use the combination of these methods. Enrolling in clinical trials of mesothelioma treatments may be beneficial for patients. Patients can find out more by speaking with a mesothelioma doctor who has treated the condition.