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Trials designed to inform clinical practice in the real world are known as pragmatic trials. They are often described by their focus on practical aspects of design that include the recruitment process and 프라그마틱 슬롯 consent, adhering and the use of standard equipment.

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A pragmatic trial that uses various investigators and participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity, which is essential for a pragmatic trial to be reliable and to reduce bias in the results is also essential. However, too much heterogeneity can result in problems with the design of the trial.

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The goal of pragmatic trials is to mimic real-life situations and achieve the highest level of validity externally. They are typically commissioned by policymakers and practitioners to help guide their decisions. They can also be used to assess the cause-effect relationship of an intervention with its outcomes. They should not, however be used to replace explanatory studies.

The concept of pragmatism is controversial and there are questions about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which confirm a physiological or clinical hypothesis and pragmatic trials, which inform the policy and practice of. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the elements of a pragmatic study that includes the recruitment, design, and delivery of the intervention and follow-up.

There is a growing trend in the number of pragmatic trials that have been published. A recent Medline search using the keywords naturalistic and pragmatic, 프라그마틱 슬롯 하는법 공식홈페이지 (dig this) limited to randomized controlled trials (RCTs), yielded 34 articles, as shown in red in Figure 2. This indicates that the health science community is becoming increasingly sensitized to the issue of pragmatic thinking. It is important to remember, however, that the majority of these studies were conducted in primary-care settings.